Petržalka, the biggest prefab panel housing estate in Slovakia, which has undergone various changes in terms of development is an important part of the capital Bratislava (it is home to a quarter of the city’s population) is also interesting for experts, self-government representatives but fist of all for locals in terms of the environment andquality of life. The aim of the paper is to briefl characterise the topical environmental problems and living conditions of population in housing estates, to characterise situation in the biggest housing estate of Slovakia and to analyse the subjective quality of life assessment of Petržalka΄s population in a broader context of Bratislava based on research accomplished in two time horizons (2003 and 2015). Results indicate the degree of importance the city’s and Petržalka΄s population give to individual quality of life domains and that Petržalka, in spite of several positive changes, is still negatively assessed. Several conclusions important for future research related to the quality of life are presented and several outputs of relevance for decision-makers seeking to improve everyday life environment in the large housing estates are identifid.