Slovakia is from the viewpoint of botany a diversified territory. Many taxa occurring here are rare, endangered, and endemic plant species. Evaluating the territory of Slovakia from the viewpoint of conservation of originality and undestroyed vegetation, occurrence of rare, endemic, and endangered plant species is able to point out the spheres where it is necessary to pay the attention to nature protection. From the viewpoint of protection of the gene-pool of our flowers its main task will be the protection of the possible highest number of endangered species in vital populations. According to the degree of endangerment is possible to calculate the coefficient of importance for each rare or endangered plant species and according to the occurrence of single taxon on a concrete territory may be calculated the index of importance from the viewpoint of rare and endangered plant species. On the basis of this index, the index of endemism and extinction, the index of protection of single areas of Slovakia may be calculated.